Q6) H right adrenal gland
A = stomach
B = pancreas
C = abdominal cavity (greater peritoneal sac)
D = spleen
E = retroperitoneal / pararenal fat
F = spinal nerve ?
G = rib
H = right adrenal gland
I = liver
http://www.authorstream.com/presentation...owerpoint/
Q13) FF = GFR/RPF
GFR = creatinine clearance = (V * UCr)/Pcr = (1 * 100)/1
RPF = PAH clearance = (V * UPAH)/PPAH = (1 * 50)/0.1
FF = 100/500= 0.2
Q17) C frameshift mutation frequently leads to premature stop codon insertion and truncated protein synthesis...in this question most likely stop codon was created downstream of given nucleotide sequence...
A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels, ie. insertion or deletion of a number of nucleotides that is not evenly divisible by three from a DNA sequence. Due to the triplet nature of gene expression by codons, the insertion or deletion can disrupt the reading frame, or the grouping of the codons, resulting in a completely different translation from the original. The earlier in the sequence the deletion or insertion occurs, the more altered the protein produced is.
A frameshift mutation causes the reading of all codons after the mutation to code for different amino acids (with a few exceptions due to redundancy). Furthermore, the stop codon ("UAA", "UGA" or "UAG") will not be read or a stop codon could be created at an earlier or later site. The protein being created could be abnormally short, abnormally long, and/or contain the wrong amino acids. It will most likely not be functional.
(i believe explanation by goforward)
Q46) A
