NBME 4 Block 3 Q10 - hrani1130

[ArchivalUser]

A 32 year old man is receiving cisplatin following surgical excision of testicular carcinoma. interaction with which of the following cellular components is most likely responsible for the antiproliferative effect of cisplatin?

A. DNA
B. Microtubles
C. Mitochondria
D. Ribosomes
E. RNA

and why??

[ArchivalUser]

cross link DNA

[ArchivalUser]

its aa..
cisplatin is an dna alkalyating agent