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Karyotypic analysis of a spontaneously aborted fetus demonstrates trisomy of one of the
chromosomes. Which chromosome is most likely to be affected?
A. 8
B. 13
C. 16
D. 18
E. 21
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Trisomy 16 -is the most common trisomy and results in 1st trimester miscarriages.
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i m sorry ..posted wrong ans..
The correct answer is C. Approximately half of all spontaneous abortions are of fetuses with
major chromosomal defects, most commonly trisomy 16, triploidy (due to fertilization of an egg
by two sperm), and 45 X,0 (Turner's syndrome). Trisomy 16 and triploidy do not produce viable
offspring, unlike 45 X,0