micro ? - rup33

[ArchivalUser]

i think it's the coagulase positive feature of staph aures to allow cavitary lesions to form??...i'm not sure the role of coagulase...can anyone tell me?

[ArchivalUser]

Coagulase reacts with prothrombin in the blood. The resulting complex is called staphylothrombin, which causes blood to clot by converting fibrinogen to fibrin. Coagulase is tightly bound to the surface of the bacteria S. aureus and can coat its surface with fibrin upon contact with blood. It has been proposed that fibrin-coated staphylococci resist phagocytosis making the bacteria more virulent.