q.2____________? - sarim

[ArchivalUser]

On routine physical examination, a 20y/o male is found to have a scrotum lacking palpable testes, plus bilateral inguinal masses.His secondary sexual characteristics are well developed and he denies any impairment in sexual drive or performance.further evaluation reveals a very low sperm count.Which of the following is the most likely to be increased in this pt?

A-LH
B-Inhibin
C-testosterone
D-FSH

[ArchivalUser]

A..lh

[ArchivalUser]

d....There are no FSH receptors, therefore inhibit levels willbe low, resulting in low sperm count. There will be a + feedback and more FSH will be release.

[ArchivalUser]

DD

[ArchivalUser]

FSH is inc b/c no feedback inhibition by inhibin which is produced by sertoli cells od testis.

[ArchivalUser]

yes correct is "D"

cryptorchidism:

testes are located close to the body where basal body temperature will affect spermatogenesis.

Seminiferous tubules are Temperature-sensitive and this is where we got Sertolli cells-----over the period of time they atrophied and become hyalinized....so what we won't have is "INHIBIN"
---->no negative feed back on *FSH----->Increased FSH.

Leydig cells are located in the stroma and they are not temperature-sensitive....so they will continue to fxn normal-------Normal Testosterone hence normal levels of LH

-and cause of this normal testosteron levels these individuals have normal sexual drive and performance.But since Sertolli cells are down, it will cause Decrease in sperm synthesis (Infertility)