03-28-2011, 10:45 PM
what type of mutation occur in Allele "O" at Blood group determinant ABO gene Locus ? and what's the outcome? thanks
ABO gene locus..... - sarim
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03-28-2011, 10:45 PM
what type of mutation occur in Allele "O" at Blood group determinant ABO gene Locus ? and what's the outcome? thanks
03-29-2011, 02:49 AM
Hi there
The deletion causes a frameshift, and results in translation of an almost entirely different protein that lacks enzymatic activity.
03-29-2011, 09:55 AM
very good maryam
![]() and that lacking enzyme is "Glycosyltransferase".An enzyme that is expressed by "Allele A" and "Allele B" in order to form Type A and Type B antigens respectively. |
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