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08-10-2011, 11:07 PM
A 27 year old female presents with primary hypothyroidism. What hormone would show some homology with the hormone that is elevated in this woman’s serum as a result of her disease?
A - Growth hormone B - Vasopressin C - ACTH D - Oxytocin E - Luteinizing hormone F - Testosterone G - Estrogen
08-10-2011, 11:53 PM
E is the correct answer.
TSH, LH, FSH, and hCG have homologous alpha subunits. That’s why you check beta subunits in laboratory test. This woman has primary hypothyroidism which results in elevated TSH levels and decreased levels of free T4, total T4, and T3 uptake. TSH has a homolgous alpha subunit with LH, FSH, and hCG. The beta subunit of these hormones determines its specificity. Thus, the correct answer is E, luteinizing hormone. |
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