@ meryem or sarim or anyone ----nbme 11 bl 2 qs 20 - docsmily

[ArchivalUser]

Thats a very nice explanation Sarim,Thanks....

So wat if Drug Y was a comp reversble antagonist.....then even we increase the dose efficacy wudnt hv changed in the 3rd position(Y= 10Um) ...right?

What is an inverse agonist?

[ArchivalUser]

u are welcome

@docsmily

-if "Y" were to be a "Comp reversible Antagonist'"..... then the efficacy wouldn't have changed in the 3rd graph (You are right about it)

-Inverse agonist
http://en.wikipedia.org/wiki/Inverse_agonist

-Examples of Inverse agonist
.Benzodiazepines (on GABAa receptors)
.Antihistamines

[ArchivalUser]

Got it...THX