11-13-2005, 03:50 AM
1.We all know that Activation of B Cell produces IgM ahead of IgG, but has anyone wondered why?
2.How does it relate to somatic hypermutation and affinity maturation of B Cells that occurs in lymph nodes?
3. How does this explain why booster doses are more effective than the initial vaccine?
Threading through the pathophysiology of B-Cell activation and Ig Production will cement this immunology concept in our minds better.
2.How does it relate to somatic hypermutation and affinity maturation of B Cells that occurs in lymph nodes?
3. How does this explain why booster doses are more effective than the initial vaccine?
Threading through the pathophysiology of B-Cell activation and Ig Production will cement this immunology concept in our minds better.