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Pure Red Cell Aplasia/Hypoplasia DDX - yeabiruh
#1
1-Blackfan -Diamond Anemia =due to defect of RBC progenitor cells =decreased RBC production=Short stature =triphalangeal thumbs=various renal anomalies =Increased HbF=Increased MCV =Rx with Predinsone


2-Trnsient Erythroblastopenia of Childhood =post viral transient immune suppression with complete recovery=pallor after a nonspecific viral illness =Normocytic =RBC adenine deaminase normal to low =Follow CBC regularly =recovery in 1-2 months =If hemodynamic unstable give Packed RBC transfusion
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