01-16-2014, 01:32 AM
whats the difference between two???i dont seem to understand
DeNovo Mutation VS germline mosaicism - stranger016
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01-16-2014, 01:32 AM
whats the difference between two???i dont seem to understand
01-16-2014, 03:39 AM
This website might help as it talks about your question.
http://hihg.med.miami.edu/code/http/modu...essonNum=3
01-16-2014, 04:26 AM
thanx alot shineonusmle2014
now the concept is clear :-)
01-16-2014, 08:30 AM
De Novo Mutation is a new mutation,it can affect somatic cells and germline cells(gonads) in case if it is a gonad,the offspring will carry the mutated gene and if it is a somatic cell -it will result in malignancy.
Germline mosaicism is a mautation of germline cells,but there are cells with normal genes and cells with mutation,offspring outcome is unpredictable. |
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