07-22-2014, 04:15 PM
Spare receptors are evidenced by:
A. The use of competitive antagonists.
B. The inability of an agonist to fully activate the receptor.
C. Full activation of the response at agonist concentration where receptor occupancy is sub-maximal.
D. Complete suppression of the response by irreversible antagonists.
E. Reduced efficacy at high antagonist concentration.
A. The use of competitive antagonists.
B. The inability of an agonist to fully activate the receptor.
C. Full activation of the response at agonist concentration where receptor occupancy is sub-maximal.
D. Complete suppression of the response by irreversible antagonists.
E. Reduced efficacy at high antagonist concentration.