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An investigator is designing a
randomized, double-blind, placebocontrolled
clinical trial to see whether
vitamin E will prevent lung cancer.
Which technique is likely to
maximize compliance with the allocated
regimen?
a. Using the placebo
b. Performing a run-in phase
c. Using intent-to-treat analysis
d. Double blinding the study
e. Limiting the number of subjects
enrolled.
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E
limiting the number of subjects will maximize the complaince to study regimen
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@forumfriends
I think you posted in another thread that complaince is maximized by performing run -in phase .....
please explain
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ans-b
In order to maximize compliance, a researcher can assess the compliance of subjects
by giving them either the active or inert medication for a certain period of
time, before the randomization for the study has occurred. Noncompliant
persons can be dropped from the entire study population and the compliant
persons are then randominzed to receive either active or inert medication
(placebo).
Choice e
limiting the number of subjects will maximize the complaince to study regimen
But how would you predict that all of your enrolled subject would be compliant.Hence to reduce drop out in clinical trial, run - in phase is done.
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@forumfriend ,thanks for Q.
I hadn't heard these terms.
actually I search internet to answer them.
where can I read these terms and other similar things?
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thank you forumfriends
I wasnt sure about my answer,
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I got this term from pretest.
you all are doing great!
thanks
