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q12! - sarim
#1
A research study is done to determine if intravenous (IV) ibandronate sodium (Boniva) will decrease the incidence rate of hip fracture in perimenopausal women. There are 2600 women in the ibandronate sodium group of whom 130 develop hip fractures. Of the 2600 women in the placebo group 260 develop hip fractures. Based on these data, how many women need to be treated with ibandronate sodium to prevent one hip fracture?

A- 1
B- 5
C- 10
D- 15
E- 20
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#2
1/ARR
1/260/2600-130/2600=2600/130=20
E
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#3
We
1/0.1-0.05 : 1/0.05 : 20
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#4
EEEE
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#5
NNT = 1 / ARR

Since the data is not given in % and both groups have equal # of Subjects i.e. each group has 2600 study subject, we can use the formula as:

NNT = 2600 / ARR
..... = 2500 / 260 - 130
..... = 2600 / 130
..... = 20

Thanks.
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#6
thanks sarim Smile
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