11-26-2015, 07:05 AM
taken from Archer Qbank:
A 24 year old woman is evaluated for a history of chronic anemia. Her history is significant for anemia for the past 7 years. She has been treated with oral iron supplements in the past with out any response. She denies any gastrointestinal bleeding. Her menstrual cycle is 3 days in duration and her menses have been scant for the past 5 years. There is no family history of anemia or bleeding disorder or cancer. Physical examination is unremarkable. Laboratory investigations reveal :
Hemoglobin : 10.6gm%
MCV: 68fl ( normal 80 to 100)
WBC : 8.8K/μl
Platelets: 230k/μl
Red Cell Distribution Width : 12.8% ( 10.2 to 14.5%)
Reticulocyte count : 6% ( normal 0.5% to 1.5%)
Which of the following are most helpful in identifying the accurate diagnosis for this patient’s anemia ( not necessarily the initial step) ?
A) Serum ferritin
B) Bone marrow biopsy
C) Direct Coombs’ test
D) Hemoglobin Electrophoresis
E) Anti-endomysial antibodies
A 24 year old woman is evaluated for a history of chronic anemia. Her history is significant for anemia for the past 7 years. She has been treated with oral iron supplements in the past with out any response. She denies any gastrointestinal bleeding. Her menstrual cycle is 3 days in duration and her menses have been scant for the past 5 years. There is no family history of anemia or bleeding disorder or cancer. Physical examination is unremarkable. Laboratory investigations reveal :
Hemoglobin : 10.6gm%
MCV: 68fl ( normal 80 to 100)
WBC : 8.8K/μl
Platelets: 230k/μl
Red Cell Distribution Width : 12.8% ( 10.2 to 14.5%)
Reticulocyte count : 6% ( normal 0.5% to 1.5%)
Which of the following are most helpful in identifying the accurate diagnosis for this patient’s anemia ( not necessarily the initial step) ?
A) Serum ferritin
B) Bone marrow biopsy
C) Direct Coombs’ test
D) Hemoglobin Electrophoresis
E) Anti-endomysial antibodies