12-09-2015, 02:10 PM
A previously healthy 18-year-old woman comes to the physician because of a 3-day history of pain with urination and urinary frequency and urgency. Physical examination shows mild tenderness over the suprapubic region. A urine culture grows an organism that is lactose fermenting and spot-indole test positive. The organism is resistant to ampicillin but sensitive to ceftriaxone. Which of the following is the most likely mechanism of antimicrobial resistance exhibited by this organism?
A)Alteration of the existing penicillin-binding protein
B)Changes in porin
C)Efflux Pumps
D)Elaboration of a new penicillin-binding protein
E) b-lactamase production
A)Alteration of the existing penicillin-binding protein
B)Changes in porin
C)Efflux Pumps
D)Elaboration of a new penicillin-binding protein
E) b-lactamase production