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These r Q without available ans.
1- Which of the following has the least cholenergic effect
a) Imipramine
b) Prozac (fluexitine)
c) nortriptyline
d) duxepine
e) amitryptaline
2.which of the following does not cause dependence
a) barbiturates
b) diazepam
c) buspirone (buspar)
d) methadone
e) alprazolam (xanax)
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I think its Prozac.Amongst SSRIs Paroxetine has anticholinergic effects rest of SSRIs dont have antichol. effects.
Amongst TCAs,desipramine has the least antichol effect followed by nortriptyline.
The antichol effect of Paroxetine is 1/5th that of nortriptyline.So U could imagine the amt of antichol effects TCAs have.Worse seen with IMN,AMN and clomipramine.
For qn2 I think it is Buspirone.Rest all have dependance potential.Thats the reason people on long term BZDs can be gradually shifted to Buspirone.
Any comments welcome.
BB
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1.atypical anticycotics!what is generic name of duxepine?
2.is it buspirone
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ans: 1. B, 2.C
Your expl 's great, Badaribrao. Could u pls help w the other Qs about psychi & drugs.
Thank u.
To att: sorry, typo, not "duxepine" but Doxepin.
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YES FLUOXETINE IS ASSRI IT HAS SEXUAL SIDE EFFECT / SLEP DISTURBANCES BUT NO CHOLINERGIC EFFECT/
AND BUSPIRONE CAN CAUS SEIZURE IN SEIZURE PRONE AND TAKES AONG TIME TO WORK BUT T HAS GOT LEAS SIDE EFFECT AND DOESNOT CAUSE DEPENDANCE.
