path Q - kashmala

[ArchivalUser]

Following penicillin Tx for pneumococcal pneumonia,a pt develops a palpable purpuric rash.Biopsy of the rash demonstrates vasculitis with hemorrhage into the skin.The involved artererioles n venules show fibrinoid necrosis n aneutrophilic Infiltrate into the wall.many of the neutrophil r fragmented.Diagnosis.
A.Allergic angiomatosis n angiitis
B.Giant cell arteritis
C.leucocytoclastic angiitis
D.polyarteritis nododsa
E>wegener's granulomatosis

[ArchivalUser]

C.

Palpable purpura = small vessel immune complex disease (thanks, goljan!)

beta-lactams are known to cause leucocytoclastic angiitis.

[ArchivalUser]

Thanks Goljan n goober
u r right