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PDH deficiency - calmer
#1
why give lysine and leucine in diet....i know they r ketogenic but so what.....

please help
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#2
http://www.pnas.org/cgi/content/full/101/13/4584
this is wat i found on google.
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#3
To rescue the deficiency, we added ketogenic substrates to the water in which the embryos develop. This treatment successfully restored vision, promoted feeding behavior, reduced lactic acidosis, and increased survival. Our study demonstrates an approach for establishing effective therapies for PDH deficiency and other congenital diseases that affect early embryonic development.

ITS FORM THE ABOVE MENTIONED LINK
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#4
thanku Kash.....hopefully its so rare they wont ask the specifics on the test....
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#5
TAKE A LOOK AT THE DIAGRAM GIVEN IN TIS LINK...u will figure it out Y ketogenic diet ievn to pt with PDH deficiency
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#6
oh yes.....eureka!!!
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#7
calmer u ask v interesting n useful Qs just like med boards
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#8
i just reading FA right now and didnt get concept....shud know everything by now yet feel like i know nothing...mind frozen over and scared...
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#9
yeah same here i just cant adjust myself to FA ...relax n u need to calmmm down....trsut me u r more than fine.
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#10
few points about leucine and lysine..


leucine.......

1... is needed for growth in infants

2.. for maintaing nitrogen balance in adults

3....during starvation and stress leucine is used for synthesis of sugar in liver.

4... in infection it helps in healing.

5...leucine regulates protein synthesis in adipose tissue.

6...it helps maintain the muscle mass

7...its important for increased production of GH



now about lysine........


1...lysine is important for growth and bone development in children

2...it helps the body to absorb calcium and if deficient may cause osteoporosis

3...it combines with vitamin c and enhnace the formation of collagen.

4... its important for those who are recovering from surgery or sports injury

5...it interferes with herpes virus replication>>> hence used for cold sores

6...lysine when combined with arginine can stimulate the release of human growth harmones

and so growth harmone increases the rate at which the fat is burnt for energy.

7...it also relieves migraine headaches

8...deficiency of lysine interferes with carnitine synthesis and have adverse impact on fat

metabolism for energy!

this may not be an answer to ur question...but it does have some relevance!
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