03-17-2007, 11:58 AM
A 13-year-old girl is brought to the doctor™s office by her anxious parents. They are very concerned about the change in her urine color; in fact, it seems that there is blood in it. The child has been in good health except for a recent respiratory tract infection. Physical examination reveals mild edema in the lower extremities and increased blood pressure. Examination of the skin is normal. Serum creatinine and blood urea nitrogen are also normal. Examination of the urine reveals gross hematuria and elevated protein. Antistreptolysin O assays are negative. Histologic examination demonstrates mesangial proliferation. Immunostaining is positive for deposition of IgA, C3 and properdin.
Which of the following is the most likely diagnosis?
(A) Acute post streptococcal glomerulonephritis
(B) Alport syndrome
© Berger disease
(D) Henoch-Schönlein purpura
(E) Minimal change disease
Which of the following is the most likely diagnosis?
(A) Acute post streptococcal glomerulonephritis
(B) Alport syndrome
© Berger disease
(D) Henoch-Schönlein purpura
(E) Minimal change disease