04-01-2007, 07:51 PM
kashmala, I posted already the answer
cholecystectomy - saonew
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04-01-2007, 07:51 PM
kashmala, I posted already the answer
04-02-2007, 06:49 AM
why everyone pick C, but no explanation?
It's from Kaplan Q book?
04-02-2007, 07:59 AM
thanks saonew..sory cudn c u already posted it.
golemed gentamicin is aminiglycoside...AG s r nephrotoxic
04-02-2007, 08:25 AM
Ans should be C as it is
as for A drugs do not destruct glomeruli they effect either interstitial tissue causing acute interstitial nephritis as seen by Aspirin,ibuprofen, papillary necrosis [anaelgesics etc] or they do Acute tubular necrosis[as seen by antibitics] So A is out, B In presence of gentamicin i am not gonna pick cephalothin as a cause of acute renal failure,Very high doeses can cause tubular necrosis[proximal] D-renal artery occlusion should show some Hypertension that is not mentioned. E- sepsis should also consumption of coagulation factors and some bleeding so answers go in favor of CCC that can easily cause acute tubular necrosis leading to high bun and creatinine due to decrease clearance of creatinine [though they both will be high in every cause leading to malfunction of kidney[damage to kidney it self either due to low blood supply,sepsis, tubular necrosis etc.] And another point is Gentamicin along with cephalothin will not increase chances of acute renal failure but cephalothin is protective against it's lipid peroxidation effect due to production of free radicals by gentamicin. |
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