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q ???? NBME -
#1
pern

a 4-YEAR-old girl is brought to the emergency department bcause of a 5-day history of fever,diffuse abdomnal pain,nausea,vomiting,and diarrhea. Examination shows petechia,hepatomegaly , and splenomegaly. Hb concentration is 8.7 g/dl and paltelet count is 60.000/mm3 . A peripheral blood smear shows erythrocyte fragmentation . Which of the following renal findings is most likely to be associated with her condition?

A- glomerular crescent formation
B- IgG-associated glomerular basement membrane antibody
C- membranoproliferative glomerulonephritis
D- narrowing of the capillary wall by fibirn deposition
E- periglomerular granuloma with giant cells
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#2
kiddyfriend

D

The child has HUS and that's related to fibrin deposits and edematous endothelium.
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#3
pern

Yes I agree , the child has a HUS and this disease cause renal failure , right ............! so this is the change in renal biopsy....................tk
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#4
apr - aprguez2001

i think is D too
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#5
juhi

D for sure
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