NBME 3, ans seems not correct, anyone plz - usmleblockbuster
|
NBME 3, ans seems not correct, anyone plz - usmleblockbuster
|
01-08-2009, 04:28 PM
an acute bilateral extensive lesion of reticular formation of the tegmentum of midbrain is likely to result in which of the following ?
1. Insomnia 2. Intractable pain 3. Loss of conciousness 4. Narcolepsy 5. Rapid eye movement
01-08-2009, 04:56 PM
reticular formation is for alertness and activity, any lesion in that ----loss of conciousness. what is your choice?
01-08-2009, 05:06 PM
I was thinking of narcolepsy as NE and serotonin depletion results in REM sleep ....Locus cearuleus is responsible for arousal ..........
01-08-2009, 07:58 PM
The reticular formation is a poorly-differentiated area of the brain stem, centered roughly in the pons. The reticular formation is the core of the brainstem running through the mid-brain, pons and medulla. The ascending reticular activating system connects to areas in the thalamus, hypothalamus, and cortex, while the descending reticular activating system connects to the cerebellum and sensory nerves.
The reticular formation is an important regulator in the autonomic nervous system for such processes as respiration rate, heart rate and gastrointestinal activity. It also plays an important role in sleep and consciousness as well as modulation of pain. The reticular formation not only appears to control physical behaviors such as sleep but also has been shown to play a major role in alertness, fatigue, and motivation to perform various activities. Some researchers have speculated that the reticular formation controls approximately 25 specific behaviors, including sleeping, walking, eating, urination, defecation, and sexual activity. Mass lesions in the brain stem cause severe alterations in level of consciousness such as coma due to their effects on the reticular formation. Bilateral damage to the reticular formation of the midbrain may lead to a coma or death. LESIONS in the reticular formation have been found in the brains of people who have post-polio syndrome, and some imaging studies have shown abnormal activity in the area in people with chronic fatigue syndrome, indicating a high likelihood that damage to the reticular formation is responsible for the fatigue experienced with these syndromes. |
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