NBME-t5-b3-#19 - usmlejan2008

[ArchivalUser]

# after an orthopaedic surgical procedure, a 48 year old woman does not breathing spontaneously, tubocurarine was used for muscle relaxation, stimulation of ulnar nerve shows continued neuromuscular blockade, to speed recovery of motor function while minimizing unwanted effect, the most appropriate therapy is atropine and which of following other drugs.
A. carbochol
B. neostigmine
C. praldoxime
D. succinylcholine
E. trimethaphan

[ArchivalUser]

B. neostigmine

[ArchivalUser]

why not praldoxime. M-blockers such as atropine, plus pralidoxime ( 2-PAM), may regenerate AChE,particular at NMJ

[ArchivalUser]

Patient was under tubocurarine, neo is an antidote but not Pralidoxime for tubocurarine.