03-27-2010, 10:21 AM
34 y/o cardiac transplant patient treated with cyclosporine and prednisone experiences a decline in renal function, He states that has been drinking more grapefruit juice recently, Grapefruit juice influences drug toxicity through which of the following mechanism
A:Alteration of gastric acidity
B:inhibition of intestinal enzymes
C:modification of transmembrance drug transport
D: Reduction of plasma protein binding
E: pharmacodynamic protentiation
A:Alteration of gastric acidity
B:inhibition of intestinal enzymes
C:modification of transmembrance drug transport
D: Reduction of plasma protein binding
E: pharmacodynamic protentiation