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nbme3- 30 - ggccjj
#1
30. Two brothers, aged 26 and 28 years, have similar disorders. Both of their histories include blue sclerae at birth, joint hypermobility, easy bruising, and moderate bilateral hearing loss. Each has had about 20 fractures since birth, all of which have healed rapidly and without deformity. Their symptoms are most likely caused by a defect in the synthesis of which of the following compounds?
A. Hydroxyapatite
B. Hydroxyproline
C. Procollagen
D. Prothrombin
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#2
this is osteo. imperfecta. defect in procollagen. choice C
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