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Quinolones vs. Fluoroquinolones? -

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Quinolones vs. Fluoroquinolones? -
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#1
07-08-2004, 01:14 PM
ahdy2000


are they the same? they can't be...

is DNA gyrase also a topoisomerase?
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#2
07-08-2004, 01:21 PM
Iceman

the enzyme is the same yes. It says so in the Pharm section
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#3
07-08-2004, 01:22 PM
ahdy2000


so do they do the same thing?...
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#4
07-08-2004, 01:32 PM
mash

DNA gyrase is type topoisomerase II in bacteria...it requires ATP whereas topoisomeraseII does not
DNA gyrase adds negative supercoils in bacterial DNA in addition to relieving positive supercoils
Topoisomerase II relieves positive supercoils only

fluoroquinolones target bacterial DNA gyrase
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#5
07-08-2004, 06:05 PM
docespy - docespy

same thing quinolones is for short.
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