phys q- help me out - yesican2010

[ArchivalUser]

which of the follow procedures is most likely to increase the serum aldosterone levels in an experimental subject?
a. administration of angiotensin converting enzyme inhibitor
b.Increase in sodium intake
c.inhibition of ACTH secretion
d. intravenous administration of 0.9% saline
e.restriction of water intake

Please explain your answer

[ArchivalUser]

restriction of water intake... restricted water intake --> decreased volume---> low pressure in glomerulus---> low filtration--> low sodium delivery to macula densa cells--> renin secretion by JG cells---> Increased Angiotensin II---> increased aldosterone... also: low volume--> carotid baroreceptors--->sympathetic outflow---> increased renin release (beta 1) then same as previous

[ArchivalUser]

EEEEEE

[ArchivalUser]

many thanks guys. I get it now