02-15-2011, 12:30 PM
A newborn has generalized defects in his limb development with fusion and malformation of his fingers and toes. An embryologist and a clinician investigate the patterning of the child’s limbs. They determine that there is a problem with the anterior-to-posterior axis formation.
A.....BMP
B.....FGF
C....HOX
D....SHH
E....TGF-BETA
A.....BMP
B.....FGF
C....HOX
D....SHH
E....TGF-BETA