OLD Q BANK:q35 - hallucination

[ArchivalUser]

A is the correct answer.renal failure--->creatinine clearance is index of renal function and it will be dec.

[ArchivalUser]

hallucination more explanation will be helpful. Thanx.

[ArchivalUser]

Renal failure---> GFR decreased.

Because Creatinine clearance, in clinical practice, is considered GFR. So A is correct.

If the ans choices have Inulin clearance, choose it.

[ArchivalUser]

The correct answer is A. Polycystic kidney disease leads to progressive decrements in renal function,
eventually resulting in renal failure (evidenced by the increased BUN and creatinine). These abnormalities are
caused by a reduction in glomerular filtration rate (GFR), which produces a decrease in creatinine clearance.
The production of creatinine, a waste product of metabolism, bears a direct relation to the muscle mass of an
individual and is independent of renal function. Because creatinine is freely filtered by the glomerulus, but not
secreted or reabsorbed to a significant extent, the renal clearance of creatinine is approximately equal to the
GFR. Therefore, creatinine clearance is commonly used to assess renal function in the clinical setting.
The extracellular sodium concentration (choice B) is not expected to change significantly in this patient.
Glucose (choice C) is not normally excreted, so glucose clearance is normally zero. Thus, is not possible for
glucose clearance to be decreased.
Plasma creatinine concentration (choice D) increases when GFR decreases.
Inulin clearance is used to estimate GFR. However, inulin is foreign to the body, and inulin plasma levels
(choice E) are normally zero.