03-11-2006, 11:59 AM
6. A 35-year-old woman, gravida 2, para 2, comes to the physician for preconceptional counseling. She has an 8-year-old daughter and a 5-year-old son. Both have mild developmental delay. The woman's brother, aged 32 years, has mild mental retardation and fragile X syndrome. Which of the following is the most likely cause of the developmental delay in this woman's children?
A. Chromosomal aneuploidy
B. Expansion of trinucleotide repeat
C. Imprinting
D. Uniparental disomy
E. X chromosome deletion
7. A 62-year-old man has sudden onset of left hemiparesis. A CT scan of the head shows a localized region of cortical infarction. Six months later, which of the following cells are most likely to be observed adjacent to the lesion?
A. Ependymal cells
B. Fibroblasts
C. Glial cells
D. Multinucleate giant cells
E. Myofibroblasts
F. Neutrophils
8. A 45-year-old woman remembers being sexually abused as a child by her older brother. She draws on her childhood experiences to express intense emotions in her work as an actor. This use of her childhood experiences is most illustrative of which of the following coping mechanisms?
A. Denial
B. Displacement
C. Dissociation
D. Isolation
E. Projection
F. Reaction formation
G. Regression
H. Repression
I. Somatization
J. Sublimation
9. A 1-year-old boy is brought to the emergency department because he is having difficulty breathing after drinking water that contains nitrate. He is cyanotic. Blood drawn for laboratory studies is chocolate-colored. His hemoglobin most likely has which of the following properties?
A. Decreased glycosylation
B. Increased binding of 2,3-bisphosphoglycerate
C. Increased proportion of Fe3+
D. Presence of Beta subunits only
E. Sickle cell mutation
10. After intravenous administration of morphine to a population of patients, the incidence of respiratory depression increases as the dosage increases. If naloxone is administered before the morphine, which of the following solid lettered curves represents the effect of naloxone on the percentage of patients with morphine-induced respiratory depression?
A. A
B. B
C. C
D. D
A. Chromosomal aneuploidy
B. Expansion of trinucleotide repeat
C. Imprinting
D. Uniparental disomy
E. X chromosome deletion
7. A 62-year-old man has sudden onset of left hemiparesis. A CT scan of the head shows a localized region of cortical infarction. Six months later, which of the following cells are most likely to be observed adjacent to the lesion?
A. Ependymal cells
B. Fibroblasts
C. Glial cells
D. Multinucleate giant cells
E. Myofibroblasts
F. Neutrophils
8. A 45-year-old woman remembers being sexually abused as a child by her older brother. She draws on her childhood experiences to express intense emotions in her work as an actor. This use of her childhood experiences is most illustrative of which of the following coping mechanisms?
A. Denial
B. Displacement
C. Dissociation
D. Isolation
E. Projection
F. Reaction formation
G. Regression
H. Repression
I. Somatization
J. Sublimation
9. A 1-year-old boy is brought to the emergency department because he is having difficulty breathing after drinking water that contains nitrate. He is cyanotic. Blood drawn for laboratory studies is chocolate-colored. His hemoglobin most likely has which of the following properties?
A. Decreased glycosylation
B. Increased binding of 2,3-bisphosphoglycerate
C. Increased proportion of Fe3+
D. Presence of Beta subunits only
E. Sickle cell mutation
10. After intravenous administration of morphine to a population of patients, the incidence of respiratory depression increases as the dosage increases. If naloxone is administered before the morphine, which of the following solid lettered curves represents the effect of naloxone on the percentage of patients with morphine-induced respiratory depression?
A. A
B. B
C. C
D. D