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genetics 9 - kashmala
#11
ee
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#12
correct answer is C
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#13
correct answer is C
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#14
C
Failure to find amplified product by PCR in such
a case could mean that the fetus is not affected or that
there is a full mutation that is too large to be picked up by
PCR. The next logical step is a Southern blot analysis of
genomic DNA from fetal cells. Routine karyotype of the
amniotic fluid cells is much less sensitive than a Southern
blot. Karyotype of the unaffected father cannot provide
information on the status of the FMR1 gene in the fetus,
because amplification of the trinucleotide occurs during oo-
genesis. For the same reason, PCR of mother's FMR1 gene
is of no value.
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#15
C
Failure to find amplified product by PCR in such
a case could mean that the fetus is not affected or that
there is a full mutation that is too large to be picked up by
PCR. The next logical step is a Southern blot analysis of
genomic DNA from fetal cells. Routine karyotype of the
amniotic fluid cells is much less sensitive than a Southern
blot. Karyotype of the unaffected father cannot provide
information on the status of the FMR1 gene in the fetus,
because amplification of the trinucleotide occurs during oo-
genesis. For the same reason, PCR of mother's FMR1 gene
is of no value.
Reply
#16
nice q kash Smile)
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#17
nice q kash Smile)
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#18
thanks for appreciation Smile)
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#19
thanks for appreciation Smile)
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