Try This Q - jumpingjack

[ArchivalUser]

A 24-year-old baseball player visits his doctor with complaints of right arm pain. On questioning, he states that it has hurt for several weeks but he has been ignoring it, attributing to muscle strain. Radiographic examination demonstrates an expansile, lytic proximal right humeral epiphyseal lesion. Based on the clinical, radiologic, and biopsy findings, the mass and proximal humerus are resected. On gross examination, the mass demonstrates hemorrhagic areas with multiple small spindle-shaped cells. Laboratory tests performed at the same time demonstrate normal serum and calcium levels. Which of the following is the likely diagnosis?

(A) Aneurysmal bone cyst
(B) Brown tumor
© Giant cell tumor
(D) Ewing sarcoma
(E) Osteoid osteoma

[ArchivalUser]

cc??

[ArchivalUser]

a...........

[ArchivalUser]

c.

[ArchivalUser]

ccc is correct

[ArchivalUser]

Jumpingjack:
Here is my input about Giant cell tumor:
Benign tumor derived from monocytes.
Most commonly affects women between the ages of 20 and 40.
Most commonly arises from epiphyses of long bones especially around the knee (distal femur; proximal tibia).
Often see cystic degeneration or necrosis and hemorrhage.
Large and red-brown.
Uniform oval mononuclear cells demonstrating many mitoses.
Osteoclast-type giant cells with up to 100 nuclei.
Fibrous stroma.
Joint pain and other arthritic symptoms.
Fractures.
Soap bubble appearance on radiograph.
Treatment: Surgical excision.
Very rarely becomes malignant, but is still aggressive and recurs after treatment 40-60% of the time.
Thanks for your questions and GOOD LUCK friends.

[ArchivalUser]

Very tricky qs.
Thx man.

[ArchivalUser]

thank you for explaining the Gaint cell tumor uzitaho.