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what is the mecanism by which hypokaliema ikcrease digixine toxicity?
what is the mecanism of Adenosine deaminase deficiency?Lesch-Nyhan syndrome?
Posts: 3,675,937
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Digoxine blocks the sodium potassim pump...increse intracellular sodium decreases the na-ca antiporter so there will be increse in intra cellular calcium..increasing the muscel contractility....how does hypokaliemia increase digoxine tox..is it by increasing the intra cellu na..can and hense contractility??