q6 - 2confused2bdoctor

[ArchivalUser]

7 yr. old boy has the sudden onset of dyspnea. On P.E he has T 37 C, P 95/minute, RR 27/minute, and BP 110/65 mm Hg. A head & neck CT scan shows a large soft tissue hematoma in his left lateral neck which impinges upon the pharynx and larynx. Later in life he develops hemarthroses with joint ankylosis. Which of the following laboratory profiles is most characteristic for his underlying disease?
A Increased PT, normal PTT, low Factor VIIIAHF, decreased vWFAg
B Increased PT, increased PTT, low Factor VIIIAHF, normal vWFAg
C Normal PT, increased PTT, low Factor VIIIAHF, normal vWFAg
D Normal PT, increased PTT, low Factor IX, normal vWFAg
E Normal PT, increased PTT, low Factor VIIIAHF, decreased vWFAg

[ArchivalUser]

eee

[ArchivalUser]

ccc

[ArchivalUser]

Ans. E

[ArchivalUser]

C is correct. The PTT will be increased with classic hemophilia A and Factor VIIIAHF (also called Factor VIIIC) is decreased, but vWFAg is usually normal or increased.

[ArchivalUser]

oops, i confused vWFAg with factor VIII Ag