03-26-2008, 10:44 PM
13. A 45-year-old man develops scaly red patches and
plaques that are most prominent on the trunk,extrem-
ities, and face. Skin biopsy demonstrates a malignant
dermal proliferation ofT lymphocytes with focal exten-
sion into the epidermis, sometimes with microabscess
formation. Which of the following is the most likely
diagnosis?
(A) Acanthosis nigricans
(B) Hand-Schüller-Christian disease
© Letterer-Siwe disease
(D) Mycosis fungoides
(E) Seborrheic keratosis
plaques that are most prominent on the trunk,extrem-
ities, and face. Skin biopsy demonstrates a malignant
dermal proliferation ofT lymphocytes with focal exten-
sion into the epidermis, sometimes with microabscess
formation. Which of the following is the most likely
diagnosis?
(A) Acanthosis nigricans
(B) Hand-Schüller-Christian disease
© Letterer-Siwe disease
(D) Mycosis fungoides
(E) Seborrheic keratosis