pls answer this - basalganglia

[ArchivalUser]

what will happen to the aldosterone concentration and Renin when ACE inhibitors r given?

[ArchivalUser]

1- decrease peripheral resistance
2- decrease aldosterone synthesis : decrease Na reabsorption
3- decrease renovascular resistance

[ArchivalUser]

this is q of relativity
aldosterone /renin ratio (ARR) in plasma
In particular, ß-blockers and clonidine can raise the ARR
Conversely, diuretics (including spironolactone), ACE inhibitors (ACE-Is), dihydropyridine calcium channel blockers (CCBs), and angiotensin II receptor blockers (ARBs) tend to reduce AR
CAN SAY aldosterone dec n renin increases
kindly correct me if m wrong

[ArchivalUser]

1- decrease peripheral resistance
2- decrease aldosterone synthesis : decrease Na reabsorption
3- decrease renovascular resistance

[ArchivalUser]

In that way : 1- Decrease aldosterone
2- Increase Renin : because of the decrease of aldosterone, renin will try to compensate.

[ArchivalUser]

i agree with docmedra

[ArchivalUser]

Yes, ACEI and ARB decrease ALDO but increase Renin, not by decreasing ALDO, but by the lost inhibitory effect of AngII over Renin

[ArchivalUser]

Thank u everyone