Question........... - psychmledr

[ArchivalUser]

A man was involved in a MVA and sustained injuries for which he was given 80 mg of meperidine. He developed a severe reaction consisting of tachycardia, hypertension, hyperpyrexia, and seizures. On further inquiry, the uninjured spouse revealed that the patient had been taking medication for a psychiatric condition.
Which of the following medications is most likely to cause this interaction with meperidine?

(A) Alprazolam
(B) Amitriptyline
© Lithium
(D) Mirtazapine
(E) Phenelzine

[ArchivalUser]

EE

[ArchivalUser]

aa

[ArchivalUser]

d?

[ArchivalUser]

Hi there
E..MAOI

Thank you

[ArchivalUser]

EE

thanks

[ArchivalUser]

Hi Maryam

Answer is E.

Concomitant administration of meperidine and MAO Inhibitors, such as phenelzine, will result in life-threatening hyperpyrexic reactions that may culminate in seizures or coma.

You are welcome