q..... - ahmad12801

[ArchivalUser]

In sheehan s syndrome what happens to
gonadotropin , prolactin < serum> , sodium , potassium , aldosterone
mark each one up or down arrow

[ArchivalUser]

gona-dec
pro-dec
Na-inc
K-Dec
Ald-Inc

[ArchivalUser]

sometimes hyponatremia also occurs.

[ArchivalUser]

my thinking k increase
aldosterone normal
because it depends upon mainly renin angiotensin system

[ArchivalUser]

Ahmad you may be right. This is my explanation
Here zona glomerulosa is unaffected as it is not controlled by ACTH.(Zona fasciculata and reticularis are affected—dec cortisol )
Adrenalin and noradrenalin can’t maintain BP due to lack of Glucocorticoids(permissive action)
Dec BP stimulates rennin- aniotensin –aldosterone system and leads to increase Aldosterone.

[ArchivalUser]

Sheehan syndrome will cause secondary adrenal insufficiency -dec ACTH dec cortisol-normal aldosterone since ACTH doesnt affect aldosterone-normal K-hyponatremia due to decrease free water clearance from hypocortisol and hypothyroidism