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A 59-year-old woman has been treated with ibuprofen for rheumatoid arthritis and with hydrochlorothiazide plus triamterene for hypertension for the past year. Ten days ago, she began taking an additional antihypertensive drug to gain better control of her blood pressure. Now she complains of muscle weakness, which has become progressively worse during the past 3 days. Laboratory studies show a serum K+ level of 7.8 mEq/L, and an ECG shows diminished P waves, prolonged QRS duration, and high-peaked T waves. The antihypertensive drug that was recently added to the treatment regimen was most likely
A. captopril.
B. furosemide.
C. metoprolol.
D. nifedipine.
E. prazosin
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A (captopril) is correct.
The patient™s clinical and laboratory findings are consistent with hyperkalemia. Because the patient was already taking a potassium-sparing diuretic (triamterene) and a nonsteroidal anti-inflammatory drug (ibuprofen) when her treatment with captopril was instituted, she was predisposed to the development of hyperkalemia.
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I think captopril because it reduces synthesis of aldesterone
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Hi Nida,
Why do u say she's taking Triamterene??????Stem says TAZ(not a K+ sparing diuretic).But Captopril possibly can cause H+k mia.Is nt it????
tx 4 Q + answer
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To pcb
"hydrochlorothiazide plus triamterene for hypertension " was metioned in the Q stem.
GL
