03-10-2009, 01:09 PM
hematin and glucose is the rx for acute intermittent porphyria....can anyone plzz explain this treatment regimen....ur ans would highly be appreciated..
treatment for porphyria? - trinath
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03-10-2009, 01:09 PM
hematin and glucose is the rx for acute intermittent porphyria....can anyone plzz explain this treatment regimen....ur ans would highly be appreciated..
03-10-2009, 01:46 PM
heme suppress -----delta ALA synthase activity;which rate limiting step enzyme.so inhibits below the reaction in porphyria synthesis-------FEEDBACK inhibition
i am not sure abt glucose
03-10-2009, 02:32 PM
both heme and glucose suppress ala synthase
03-10-2009, 05:10 PM
heme suppresses or inhibits d-ala synthase can be understood but how does glucose inhibit ala synthase...plzz explain a lil more....
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