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A 47 y.o. man with hx of DM and gallstones, comes with his doctor because of a recent 4.5 kg (10 lb) weight loss and fatty stools. Lab. shows a decreased levels of pespinogen, amylase, lipase, and glucagon. A CT scan shows a mass in the pancreas. based on this which of the following substances might be secreted by this pancreatic tumor?
A. CCK
B Gastrin
c. Intrinsic factor
D. SRIF
E. Secretin
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D-
CCK...INC. SECRETION
SECRETIN..INC. SECRETION
INTRINSIC..NOT RELATED
GASTREN INC. PEPSINOGEN
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Answer D.
Somatostatin (also known as growth hormone-inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF).
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pancreatic adenoma ---does secrete gastrin , like in zollinger ellison syndrome --you have gastrin levels above --1000.But at the same time --somatostatin does inhibit every hormone in the body --so dec all hormone levels .
somatoatin is rx of esophageal variesis and acromegaly ---octreotide.