07-12-2010, 11:06 AM
52y/o woman with ductal cell carcinoma with metastase to lung and liver died. her mother and sister were died of breast cancer. which of the molecullar abnormality is the reason?
a.amplification of HER2 gene in somatic cell
b.amplification of N-MYC in neoplastic cell
c.deletion of rb in healthy somatic cell
d. germline inactivation of BRCA1 gene
a.amplification of HER2 gene in somatic cell
b.amplification of N-MYC in neoplastic cell
c.deletion of rb in healthy somatic cell
d. germline inactivation of BRCA1 gene