Drug induced hepatic...... - leschnyhan

[ArchivalUser]

Good AAAA is correct.

Drug-induced liver disease ------> hepatocellular, cholestatic or mixed


*Hepatocellular

paracetamol

sodium valproate, phenytoin

MAOIs

halothane

anti-tuberculosis: isoniazid, rifampicin, pyrazinamide

statins, fibrates

alcohol

amiodarone

methyldopahe

*The following drugs tend to cause cholestasis (+/- hepatitis):

oral contraceptive pill

antibiotics: flucloxacillin, co-amoxiclav, erythromycin, nitrofurantoin

anabolic steroids, testosterones

phenothiazines: chlorpromazine, prochlorperazine

sulphonylureas

rare reported causes: nifedipine