03-20-2007, 04:07 PM
PENICILLIN ALLERGY
Classified as:
1. Immediate (within first hour) - Anaphylaxis, hives, wheezing.
2. Accelerated (1-72 hours later) - Urticaria is major symptom.
3. Late (more than 72 hours later) - Maculopapular reactions, drug fever, serum sickness, hemolytic anemia, leukocytopenia.
remember guys, if it is 1 or 2, then it is IgE mediated type I
If it is S/S days later, it is serum sickness typyIII, thus IgG amd/or IgM mediated.
Time issue is the key for diagonisis here
Classified as:
1. Immediate (within first hour) - Anaphylaxis, hives, wheezing.
2. Accelerated (1-72 hours later) - Urticaria is major symptom.
3. Late (more than 72 hours later) - Maculopapular reactions, drug fever, serum sickness, hemolytic anemia, leukocytopenia.
remember guys, if it is 1 or 2, then it is IgE mediated type I
If it is S/S days later, it is serum sickness typyIII, thus IgG amd/or IgM mediated.
Time issue is the key for diagonisis here