03-01-2008, 08:29 AM
Cancer genetics
Genetics FlashCard? FlashMode: Off Term Description
Neurofibromatosis type 1
GENETICS Deletion (17q11.2)
GENE NF1 (Tumor suppressor gene)
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Cancer genetics
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Neurofibromatosis type 2
GENETICS Deletion (22q11)
GENE NF2 (Tumor suppressor gene)
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Cancer genetics
Genetics FlashCard? FlashMode: Off Term Description
Melanoma
GENETICS Deletion (9p21)
GENE MTS1/MTS2/CDK41 (Tumor suppressor genes)
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Cancer genetics
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Chronic Myeloid Leukemia
GENETICS Translocation (9;22)(q34;q11)
Translocation (16;21) (p11;q22)
GENE Oncogenes: ABL (9q34.1), BCR (22q11), ERG (21q22.3), TLS/FUS (16p11)
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Cancer genetics
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Non-Hodgkin's lymphoma
GENETICS Translocation (2;5) (p23;q35)
Translocation (14;18) (q32;q21)
Translocation (3;14) (q27;q32)
Translocation (3;22) (q27;q11)
GENE Oncogenes: ALK (2p23), NPM (5q35), BCL2 (18q21.3), BCL6 (3q27)
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Cancer genetics
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Acute Myeloid leukemia
GENETICS Translocation (8;21) (q22;q22)
Translocation (6;9) (p23;q34)
Inversion (16) (p13;q22)
GENE Oncogenes: AML1 (21q22), ETO (8q22), MTG8 (8), CAN (6p23), DEK (9q34), SET
(9q34), CBFB (16q22), MYH11 (16p13.12-p13.13)
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Cancer genetics
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B-cell lymphoma
GENETICS Translocation (11;14) (q13;q32)
GENE Oncogenes: BCL1 (11q13.3), IgH (14q32)
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Cancer genetics
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Ewing's sarcoma
GENETICS Translocation (22;21) (q12;q22)
Translocation (11;22) (q24;q12)
GENE Oncogenes: ERG (21q22.3), EWS (22q12), FL11 (11q24)
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Cancer genetics
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Acute Lymphoblastic Leukemia
GENETICS Translocation (8;14)q24;q32)
Translocation (14;18) (q32;q21)
Translocation (4;11) (q21;q23)
GENE Oncogenes: MYC (8q24), BCL2 (18q21.3), MLL / ALL1 / HRX (11q23)
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Cancer genetics
Genetics FlashCard? FlashMode: Off Term Description
Burkitt's lymphoma
GENETICS Translocation (8;14) (q24;q32)
Translocation (8;22) (q24;q11)
Translocation (2;8) (p12;q24)
GENE Oncogenes: MYC (8q24), IgH (14q32), Igï¬ (22q11), Igï« (2p12)
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