08-19-2004, 08:30 AM
jaf
A 2-year-old child is seen for a welI-child visit in a pediatric clinic. Abdominal examination demonstrates a palpable, non-tender mass on the Ieft side of the abdomen. The mother had no idea the mass was present and the pediatrician did not note the presence of the mass at the child's 18-month welI-child visit. Physical examination is otherwise unremarkable.
Question 1 of 4
CT examination demonstrates an 8-cm diameter, roughly round, mass involving the lower pole of the kidney. Which of the following is the most likely cause of this mass?
A. Ewing sarcoma
B. Neuroblastoma
C. Renal cell carcinoma
D. Transitional cell carcinoma
E. Wilms tumor
Question 2 of 4
If a CT guided biopsy of the mass were performed, which of the following histological patterns would be most suggestive of the likely diagnosis?
A. Cords of clear cells with rounded or polygonal shape and abundant clear cytoplasm
B. Invasive papillary lesions with delicate connective tissue stalk covered with epithelium resembling that lining the bladder
C. Small dark cells embedded in a finely fibrillar matrix with formation of numerous rosettes
D. Triphasic pattern with tubule formation, spindle cells, and blastemal elements
E. Uniform sheets of small round cells with scanty cytoplasm
Question 3 of 4
Sometimes this child's disease occurs in association with certain congenital anomalies. Children with which of the following abnormalities at birth should be monitored for the development of this disease?
A. Aniridia
B. Coarctation of the aorta
C. Cystic hygroma
D. Parathyroid hyperplasia
E. Simian crease
Question 4 of 4
Abnormalities of which of the following chromosomes have been linked to this disease?
A. 3
B. 5
C. 11
D. 15
E. 21
A 2-year-old child is seen for a welI-child visit in a pediatric clinic. Abdominal examination demonstrates a palpable, non-tender mass on the Ieft side of the abdomen. The mother had no idea the mass was present and the pediatrician did not note the presence of the mass at the child's 18-month welI-child visit. Physical examination is otherwise unremarkable.
Question 1 of 4
CT examination demonstrates an 8-cm diameter, roughly round, mass involving the lower pole of the kidney. Which of the following is the most likely cause of this mass?
A. Ewing sarcoma
B. Neuroblastoma
C. Renal cell carcinoma
D. Transitional cell carcinoma
E. Wilms tumor
Question 2 of 4
If a CT guided biopsy of the mass were performed, which of the following histological patterns would be most suggestive of the likely diagnosis?
A. Cords of clear cells with rounded or polygonal shape and abundant clear cytoplasm
B. Invasive papillary lesions with delicate connective tissue stalk covered with epithelium resembling that lining the bladder
C. Small dark cells embedded in a finely fibrillar matrix with formation of numerous rosettes
D. Triphasic pattern with tubule formation, spindle cells, and blastemal elements
E. Uniform sheets of small round cells with scanty cytoplasm
Question 3 of 4
Sometimes this child's disease occurs in association with certain congenital anomalies. Children with which of the following abnormalities at birth should be monitored for the development of this disease?
A. Aniridia
B. Coarctation of the aorta
C. Cystic hygroma
D. Parathyroid hyperplasia
E. Simian crease
Question 4 of 4
Abnormalities of which of the following chromosomes have been linked to this disease?
A. 3
B. 5
C. 11
D. 15
E. 21