10-18-2008, 12:28 AM
C is the correct answer
This patient likely has a deep vein thrombosis (DVT). Whenever you see DVT, think Virchow's triad. Virchow's triad describes the most common causes of thrombosis - endothelial injury, stasis, and thrombophilia.
Cancer is a proinflammatory state that strongly predisposes towards thrombosis, and is an established major risk factor for DVT.
Female gender is not by itself a risk factor for DVT. However, estrogen therapy (whether OCPs or estrogen replacement) can be a risk factor in women.
Paclitaxel is an antineoplastic drug that targets microtubules, but does not predispose to thrombosis.
Knee arthritis does not predispose to DVT, unless it was so incapacitating as to lead to immobility.
Age of 47 is not a risk factor. Older age (>60) is a minor risk factor for DVT. Any unprovoked DVT in a younger person is an indication for a thrombosis workup.
This patient likely has a deep vein thrombosis (DVT). Whenever you see DVT, think Virchow's triad. Virchow's triad describes the most common causes of thrombosis - endothelial injury, stasis, and thrombophilia.
Cancer is a proinflammatory state that strongly predisposes towards thrombosis, and is an established major risk factor for DVT.
Female gender is not by itself a risk factor for DVT. However, estrogen therapy (whether OCPs or estrogen replacement) can be a risk factor in women.
Paclitaxel is an antineoplastic drug that targets microtubules, but does not predispose to thrombosis.
Knee arthritis does not predispose to DVT, unless it was so incapacitating as to lead to immobility.
Age of 47 is not a risk factor. Older age (>60) is a minor risk factor for DVT. Any unprovoked DVT in a younger person is an indication for a thrombosis workup.