08-06-2011, 10:46 PM
Mild symptoms such as pruritus and urticaria can be controlled by administration of 0.3 to 0.5 mL of 1:1000 (1.0 mg/mL) epinephrine SC or IM, with repeated doses as required at 5- to 20-min intervals for a severe reaction
REF: Harrison
so no hard & fast rule for one modality
REF: Harrison
so no hard & fast rule for one modality