06-11-2006, 10:16 AM
The correct answer is E.
Osteopetrosis (Albers-Schonberg disease) - group of hereditary diseases --- impaired osteoclast function leads to reduced bone resorption.
- Abnormal osteoclasts frequently are enlarged, with bizarre shapes
- Bones become thick and brittle
- Anemia secondary to marrow loss
- CN deficits secondary to narrowing of bony ostea
An autosomal recessive, severe form of the disease --- death in childhood.
A relatively benign, autosomal dominant form --- in adulthood.
Osteopetrosis (Albers-Schonberg disease) - group of hereditary diseases --- impaired osteoclast function leads to reduced bone resorption.
- Abnormal osteoclasts frequently are enlarged, with bizarre shapes
- Bones become thick and brittle
- Anemia secondary to marrow loss
- CN deficits secondary to narrowing of bony ostea
An autosomal recessive, severe form of the disease --- death in childhood.
A relatively benign, autosomal dominant form --- in adulthood.